Volume 11, Issue 1
Antidiabetic and Hypolipidemic Effects of Ipomea batata Fresh Leaves Extract on Alloxan Induced Diabetic Rats
Olusegun Omolade Fajana1,2*, Olasunkanmi Kayode Awote1,2, Adesegun Gideon Adeyemo1,2, and Jimoh Olamilekan Igbalaye1,2
1Cell and Tissue Culture / Drug Discovery Lab.
2Department of Biochemistry, Faculty of Science, Lagos State University, Ojo, Lagos.
DOI:10.36108/jrrslasu/4202.11.0160
Abstract
Introduction: Ipoma batata is one of the herbs used in the alternative treatment of diabetes mellitus. Aims: The present study was designed to investigate the antidiabetic and hypolipidaemic effects of aqueous extract of Ipoma batata aerial part in normal and alloxan diabetic rats. Materials and Methods: The treatment was given for 14days. After the treatment a significant reduction was observed in fasting serum glucose levels in the treated diabetics’ rats. Results: Ipomea batata treatment showed appreciable lowering of serum total cholesterol, triglycerides, Low Density Lipoprotein cholesterol, Total Cholesterol /High Density Lipoprotein Cholesterol and an increase in High Density Lipoprotein Cholesterol in the treated diabetic group. Conclusion: These results indicate that the ipoma batata leaves extract possess antidiabetic and hypolipideamic effects in alloxan-induced diabetic rats.